I have begun wrapping my cables preemptively. I find that they tend to fray where the cable enters the iPad end. So, I take about 4 inches of duct-tape and wrap it snugly.
This will hopefully help protect the cables, and they have also proven to be incredibly useful in plugging in iPads which have a Big Grips case on them. The only complaint staff have had for the Big Grips, is that the charging port is recessed in the casing, and sometimes hard to plug in.